All functions |
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Check CoCoA input |
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Create a list of MTX-related files |
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Counterfactual confounder adjustment for individual-level differential expression analysis |
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Counterfactual confounder adjustment by by Pairwise INdividual Effect matching |
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Simulate single-cell MTX data for DEG analysis |
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Simulate single-cell MTX data for eQTL analysis |
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Simulate mosaic (multi-batch) single-cell MTX data for eQTL analysis. |
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Check duplicated pairs of individuals in the matching results and take the nearest ones |
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Build sparse matrix from triplets |
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Create pseudo-bulk data by aggregating columns |
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Create pseudo-bulk data for pairwise comparisons |
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Annotate columns by marker feature information |
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BBKNN(Batch-balancing kNN) adjustment of SVD factors |
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BBKNN(Batch-balancing kNN)-adjusted SVD |
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Create an index file for a given MTX |
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Check if the index tab is valid |
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Collect row-wise and column-wise statistics |
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Take a subset of columns and create a new MTX file-set |
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Take a subset of rows and create a new MTX file-set |
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Just read the header information |
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Match the columns of two MTX files |
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Merge multiple 10x mtx file sets into one set |
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Construct a kNN cell-cell interaction network and identify gene topics |
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Read a subset of columns from the data matrix |
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Read a subset of columns from the data matrix |
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Read an index file to R |
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Simulation Poisson data based on Mu |
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Simulate sparse counting data with a mixture of Poisson parameters |
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Approximate SVD |
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Write down sparse matrix to the disk |
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A wrapper function to read a dense submatrix |
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A wrapper function to read a sparse submatrix |
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Read a vector of string names |
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Regress out covariates |
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Simulate individual-level eQTL data |
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Simulate individual-level effects by GLM |
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A wrapper function that concatenates two files vertically |
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Write matrix market file set |