All functions

check.cocoa.input()

Check CoCoA input

fileset.list()

Create a list of MTX-related files

make.cocoa()

Counterfactual confounder adjustment for individual-level differential expression analysis

make.pine()

Counterfactual confounder adjustment by by Pairwise INdividual Effect matching

make.sc.deg.data()

Simulate single-cell MTX data for DEG analysis

make.sc.eqtl.data()

Simulate single-cell MTX data for eQTL analysis

make.sc.eqtl.mosaic()

Simulate mosaic (multi-batch) single-cell MTX data for eQTL analysis.

pine.remove.duplicated()

Check duplicated pairs of individuals in the matching results and take the nearest ones

rcpp_build_sparse_mat()

Build sparse matrix from triplets

rcpp_mmutil_aggregate()

Create pseudo-bulk data by aggregating columns

rcpp_mmutil_aggregate_pairwise()

Create pseudo-bulk data for pairwise comparisons

rcpp_mmutil_annotate_columns()

Annotate columns by marker feature information

rcpp_mmutil_bbknn()

BBKNN(Batch-balancing kNN) adjustment of SVD factors

rcpp_mmutil_bbknn_mtx()

BBKNN(Batch-balancing kNN)-adjusted SVD

rcpp_mmutil_build_index()

Create an index file for a given MTX

rcpp_mmutil_check_index()

Check if the index tab is valid

rcpp_mmutil_compute_scores()

Collect row-wise and column-wise statistics

rcpp_mmutil_copy_selected_columns()

Take a subset of columns and create a new MTX file-set

rcpp_mmutil_copy_selected_rows()

Take a subset of rows and create a new MTX file-set

rcpp_mmutil_info()

Just read the header information

rcpp_mmutil_match_files()

Match the columns of two MTX files

rcpp_mmutil_merge_file_sets()

Merge multiple 10x mtx file sets into one set

rcpp_mmutil_network_topic_data()

Construct a kNN cell-cell interaction network and identify gene topics

rcpp_mmutil_read_columns()

Read a subset of columns from the data matrix

rcpp_mmutil_read_columns_sparse()

Read a subset of columns from the data matrix

rcpp_mmutil_read_index()

Read an index file to R

rcpp_mmutil_simulate_poisson()

Simulation Poisson data based on Mu

rcpp_mmutil_simulate_poisson_mixture()

Simulate sparse counting data with a mixture of Poisson parameters

rcpp_mmutil_svd()

Approximate SVD

rcpp_mmutil_write_mtx()

Write down sparse matrix to the disk

read.dense()

A wrapper function to read a dense submatrix

read.sparse()

A wrapper function to read a sparse submatrix

read.vec()

Read a vector of string names

safe.lm()

Regress out covariates

simulate_indv_eqtl()

Simulate individual-level eQTL data

simulate_indv_glm()

Simulate individual-level effects by GLM

vcat.sparse()

A wrapper function that concatenates two files vertically

write.sparse()

Write matrix market file set